To determine whether deregulation of negative regulators of NF-κB has a role in constitutive NF-κB activation in glioblastoma, we analyzed expressions of the NF-κB regulators NFKBIA, TNFAIP3, TNIP1 and TNIP2 in glioblastoma patients from The Cancer Genome Atlas (TCGA). The gene discussed is TNIP1; the disease is glioblastoma.