PSMD10 and neoplasm: An ankyrin repeat protein 9.29 which binds with high affinity to human epidermal growth factor receptor/neu (HER2/neu), a receptor tyrosine kinase overexpressed in tumor cells has been fused with AAV capsid to ablate the natural tropism and re-direct the vector to HER2 positive tumor cells (Münch et al., 2013).