Moreover, as shown in Fig. 4, HRs for OS in subgroups of age (<40 years or ≥40 years), race (white or black), gradeII, grade III and UD, ER positive, PR negative, no lymph node, surgery (yes or no) and no radiotherapy were significantly different between DCISM and DCIS. This evidence concerns the gene PGR and ductal breast carcinoma in situ.