For example, miR‐886, which targets PLK1 and TGF‐β1, was reported to be silenced by DNA hypermethylation in lung cancer (Cao et al., 2013), and miR‐29 was found to be epigenetically repressed by MYC through a corepressor complex with histone deacetylase 3 (HDAC3) and enhancer of zeste homolog 2 (EZH2) in aggressive B‐cell lymphomas (Zhang et al., 2012). This evidence concerns the gene EZH2 and lung carcinoma.