RBX1 and non-small cell lung carcinoma: These findings, together with the result that RBX1, a subunit of CRL4B that is overexpressed in a number of human tumors (Jia et al., 2009), is also targeted by miR‐194 (Chen et al., 2015), established that CRL4B and miR‐194 form a negative feedback loop in NSCLC cells (Fig. 7).