The downregulation of tumor necrosis factor receptor superfamily, member 10b protein (TNFRSF10B/TRAIL) by upregulated miR-20a [8, 19] is in line with the resistance of the PCa cell lines LNCaP, DU145, or PC3 towards TRAIL/TNFRSF10B-induced apoptosis [59] and its downregulation in PCa [60]. This evidence concerns the gene TNFSF10 and posterior cortical atrophy.