IFNA1 and infection: After infection with EK-328 strain in the high dose (106 PFU), IFN-α was detected at 10 h p.i. After injection of 106 PFU of the Absettarov strain, IFN-α appeared at 5 h p.i. followed by a 1.5-fold increase at 10 h p.i. The Absettarov strain induced higher titers of IFN-α production at all time-points.