FLT3 and acute myeloid leukemia: This information was compared with the prognostic risk factors conventionally studied for the stratification of patients into low-, intermediate- and high-risk AML (including age, leukocytosis >30,000 cells/mm3, complex karyotype and low risk translocations t(15;17), t(8;21), inv16; and high risk FLT3 ITD mutation).