IDH1 and central nervous system cancer: Moreover, the glioma patients in the same grade, IDH status, age and KPS groups could also be divided into two subgroups with different outcomes based on SND1 and β-catenin expressions, i.e., the higher their expressions were, the poorer prognosis of patients (DFS: P<0.0001; OS: P<0.0001; Figure 3E-3G, Supplementary Figure 6A and 6B, and Supplementary Figure 7A-7H).