IDH1 and central nervous system cancer: Significantly, we found that glioma patients in the same grade, IDH status, age and KPS groups could be divided into two subgroups with different outcomes based on miR-320a expression, i.e., the higher expression of miR-320a was, the better prognosis of patients (DFS: P<0.0001; OS: P<0.0001; Figure 1E-1I and Supplementary Figure 3A-3D).