CNN3 and breast cancer: Western blot data indicated that miR-1 overexpression significantly downregulated WASF2, TWF1, CNN3, TMSB4X and CORO1C (Figure 5G), showing that miR-1 could inhibit breast cancer cell metastasis by targeting the WASF2, TWF1, CNN3, TMSB4X and CORO1C genes.