With the development of high throughput chip and sequencing technology, a variety of lncRNAs have been investigated, e.g. HOX transcript antisense RNA (HOTAIR) [5], prostate cancer non-coding RNA1 (PRNCR1) [6], RNA polymerase II polypeptise E gene (POLR2E) [7, 8]. This evidence concerns the gene POLR2E and Familial prostate cancer.