H2AX and Miyoshi myopathy: Treatment with CUR at the concentration of 25 μM for 30 hours led to a significant increased phosphorylation of γ-H2AX in all MM cell lines (MM-F1, p<0.01; MM-B1, p<0.001; H-Meso-1, p<0.001; #40a, p<0.01) (Figure 2).