To verify our results that lower Hp expression is correlated with poor HCC cancer cell differentiation, we selected several markers (TWIST1, LAMB1, THY1, EZH2, SALL4, and TCF3) that are closely associated with the activation of poor HCC cancer differentiation and analyzed the Pearson correlation coefficient of each selected marker to Hp. This evidence concerns the gene TCF3 and hepatocellular carcinoma.