On the other hand, negative correlation of EZH2 (r = -0.53, p < 0.001), SALL4 (r = -0.4, p < 0.001), TCF3 (r = -0.45, p < 0.001) with Hp in high tumor Hp expression group could also be an indication of relative well cancer differentiation. The gene discussed is HP; the disease is cancer.