Makishima et al. detected SETBP1 mutations in 22 out of 152 patients with CMML [5] and Damm et al. observed SETBP1 mutations in 12 out of 195 patients with CMML and in 5 out of 222 patients with MDS [6]. The gene discussed is SETBP1; the disease is myelodysplastic syndrome.