LRRC2 and dilated cardiomyopathy: To address a possible link to human disease, we queried LRRC2 expression in a left ventricle-derived RNASeq dataset derived from dilated cardiomyopathy (n = 140) and healthy control (n = 110) subjects and observed elevated LRRC2 transcript expression in the patient cohort (Fig 4B, middle panel).