AR and posterior cortical atrophy: On another note, two (AR and IGF1) out of three genes in the Androgen Receptor (AR) pathway that were up-regulated in MDA-PCa-2b cells (log(dMDA/DU) ≥ 0.585) showed specific down-regulation after miR-24 transfection (logFC ≤ –0.415) (Supplementary Figure 3).