IGF1 and posterior cortical atrophy: In addition to the reductions of target genes by miR-24 transfection, our linear regression analysis with TCGA database indicates inverse correlation between miR-24 and each three target genes (AR, IGF1 and VEGFA), and supports that miR-24 may directly control these three oncogenes in human PCa (Figure 5B, 5C and 5D).