AKT1 and posterior cortical atrophy: Genes in the Transcription Factor, and PI3K/AKT pathways were also up-regulated in MDA-PCa-2b and decreased by miR-24 over-expression (4 out of 7 and 3 out of 5, respectively) (Supplementary Figure 3), while miR-24 has not decreased these genes in DU-145.