DSEL (synonym: C18orf4) which encodes the dermatan sulfate epimerase-like protein that shows a significant homology with DSEP [31, 32] (synonym: SART-2), a squamous cell carcinoma antigen that can induce HLA-24-restricted and tumor-specific cytotoxic T-lymphocytes [33]. The gene discussed is DSE; the disease is squamous cell carcinoma.