Moreover, while RH cells were able to form tumor masses in 30 days, when inoculated into the posterior flank of syngeneic rats, RNT cells were completely devoid of tumorigenic ability (Figure 9B, 9C); these tumors showed morphological features of HCC (Figure 9D) and were strongly positive for KRT19 (Figure 9E), thus maintaining the same features of the cells grown in vitro. The gene discussed is KRT19; the disease is hepatocellular carcinoma.