All adenomatous lesions and cancers expressed EGFR with higher proportions of labeled cells per sample (Adenomas: 54.9% grade 2–3; cancers: 100% grade 3), compared to hyperplastic polyps (grade 2–3: 0%) or normal colonic mucosa issued from the control group (grade 2–3: 9.4%–28.3%) (p < 0.01). Here, EGFR is linked to cancer.