The AUROC of GP73 was 0.527 (95% CI: 0.542–0.601) to distinguish HCC patients with cirrhosis from cirrhosis patients, and was 0.538 (95% CI: 0.520–0.557) when to distinguish HCC patients without cirrhosis from pre-cirrhotic CLD patients, respectively (Figure 3C, 3D). The gene discussed is GOLM1; the disease is Cirrhosis.