VAV2 and obesity due to melanocortin 4 receptor deficiency: There are also differences in VAV2 rs602990 SNP genotypic distribution between obese (BMI > 30) (n = 123) and non-obese (BMI 25–30) patients (n = 197) in the recessive model, where being carrier of the T allele is associated with an increased risk of obesity (Table 7) and a decreased average and minor retinal artery caliber (Table 8).