IL1B and colorectal carcinoma: Remarkably, the interaction of IL1B-CGTC haplotype copies with locus-specific African ancestry was associated with CRC (p = 0.03; Model 6a); nevertheless, when testing only the main effects of all three variables, only locus-specific African ancestry was found to be associated with CRC (OR 3.58; 95% CI 0.97–13.30; p = 0.06; Model 7a).