IL1B and colorectal carcinoma: In the conditional haplotype tests controlling for the IL1B-511/IL1B-31 SNPs, we confirmed that the IL1B-1464G allele (haplotype N°3) was a risk factor for CRC compared to having the IL1B-1464C allele (haplotype N°4) (subnull p = 0.04; likelihood ratio test: chi-square = 5.63, Degrees of freedom (df ) = 2, p = 0.06).