In situ examination of tumor tissues by IHC analysis demonstrated active EGFR (pEGFR) expression in both HPV‐positive and negative tumors with higher pEGFR positivity associated with HPV‐negative tumors (P = 0.033) and it negatively correlated with HPV infection status (OR – 0.27) (Fig. S5B; Table 2). The gene discussed is EGFR; the disease is neoplasm.