CD4 and Alzheimer disease: Figure 1 presents the CD4 cell count at HIV diagnosis of all patients included. Overall, the median CD4 cell count was 206 cells/μL (IQR 89 - 381). According to our definition, 1,810 (48.7%) patients had AD and 858 (23.1%) had LP; in total 71.8%. The median CD4 cell count at presentation varied during the study period (Figure 2) with the lowest measurements in 2007 (146 cells/μL) and the highest in 2011 (229 cells/μL, p<0.01).