Within the group of TH2 cytokines, we found there was a significant increase of IL-10 production in patients at stroke onset compared to both Healthy and Hospital controls, and this stroke-induced elevation of IL-10 was observed for up to 3 months following the stroke event (Figure 4A), a trend that is very similar to the temporal profile of iNKT cell activation after stroke. The gene discussed is IL10; the disease is stroke disorder.