In the clinic, patients with ischemic strokeadministered thrombolytic agents such as tPA have a rather high probability ofhemorrhage transients, and miconazole may protect patients from such transients.Based on work in zebrafish and rats, we propose that miconazole may be a goodcandidate for these types of prevention of hemorrhagic stroke. The gene discussed is PLAT; the disease is hemorrhagic stroke.