Besides the frequently altered, previously reported loci (chromosomes 7p11 and 12q13-15) [25], our analysis also revealed novel loci on chromosomes 1p36 (harboring MTOR, n = 1), 1q32 (harboring MDM4, n = 2), 6q21 (harboring the autophagy protein 5 gene, ATG5, n = 1) and 16q13 (harboring a cluster of metallothionein (MT) genes, n = 1) to be amplified in GBM samples (Fig. 4a–d; Additional file 2: Figures S2 and S3). Here, MDM4 is linked to glioblastoma.