The correlation between AC068491.1.1 and IGFBP3 differed between normal and colorectal cancer tumor samples; in normal samples, AC068491.1.1 and IGFBP3 were negatively correlated (r = –0.49, P = 0.038), while in colorectal cancer samples they were positively correlated (r = 0.69, P = 0.001). The gene discussed is IGFBP3; the disease is colorectal cancer.