GPT and hepatocellular carcinoma: Multivariate analysis confirmed that the presence of either sP203Q or sS210R was independently associated with a higher probability of developing HCC (adjusted Odd-Ratio [95% C.I.]: 12.0 [1.6-78.8], P=0.02), after correction for patients' age, gender, HBV genotype, serum HBV-DNA, ALT and AST (Table 2).