This result corresponds with previous studies showing that PD-L1 is associated with poorer prognosis in patients with NSCLC, [6, 30] esophageal carcinoma, [31] gastric carcinoma, [32] pancreatic carcinoma, [33] hepatocellular carcinoma, [34] renal cell carcinoma, [11] and ovarian carcinoma [35]. Here, CD274 is linked to carcinoma of esophagus.