Somewhat surprisingly, we found that the steady state levels of MYC vary in NSCLC cell lines regardless of the presence or absence of oncogenic KRAS mutations, ranging from the levels seen in normal cells (e.g. NIH3T3 and IMR90 cells, around or less than 5,000 molecules per cell) to the levels seen in many tumor cells (e.g. HeLa cells, >30,000 molecules per cell) [26, 27]. The gene discussed is MYC; the disease is non-small cell lung carcinoma.