PLK1 and ovarian cancer: These included two chemokine receptors (CCR), CCR9 and CCR2, which have been implicated in driving oncogenesis and shown to induce apoptosis when depleted in cancerous cells [28, 29], Testis expressed 14 (TEX14) that is a PLK1 regulated protein [30], as well as Wnt inhibitory factor 1 (WIF1), which antagonises Wnt signaling [31] and may therefore be important for the control of the pathway in ovarian cancer cells.