Dt81Hepa1-6 EpCAM+high cells were associated with higher tumor load than Dt81Hepa1-6 EpCAM+low cells (Tumor load (Fig 5C): 1093±74 tumors vs 473±100 tumors P<0.01) and AFP levels (Fig 5D: 877.3±140.7 fold changes vs. 279.6±36.4 fold changes; P<0.01). This evidence concerns the gene AFP and neoplasm.