Visual analyses of 37 NKL homeobox gene expression profiles for 117 T-ALL patient samples (GSE26713) confirmed enhanced transcript levels of NKL homeobox oncogenes including TLX1, TLX3, NKX2-1 and NKX2-5 and additionally identified novel members showing aberrant expression levels in patient subsets including DLX1, NKX2-3 and TLX2 (S2 Fig). Here, NKX2-3 is linked to acute lymphoblastic leukemia.