ABCB1 and major depressive disorder: Importantly, the rs2032582 (G2677T/A), rsl045642 (C3435T), and rsll28503 (C1236T) are the common and functional mutation position of the ABCB1 genetic polymorphism.[13–15] In addition, Huang et al[16] reported that ABCB1 genetic polymorphisms might be associated with SSRIs treatment response in the Chinese Han depression population.