Our previous studies demonstrated that Dclk1 overexpression is correlated with intestinal cancer progression and that silencing Dclk1 decreased the number and size of polyps, adenoma, and adenocarcinoma, suggesting that Dclk1 plays an important active role in intestinal tumorigenesis [18, 28, 39, 40]. Here, DCLK1 is linked to adenocarcinoma.