MTOR and cancer: Besides, AURKA could contribute to cancer cell survival via increasing anti-apoptotic modulators (Bcl-2 [70], MCL-1 [71]) and decreasing pro-apoptotic regulators (Bax [70], Bim [72], PUMA [73]) or suppressing autophagy through activating mammalian Target of Rapamycin (mTOR) signaling [74].