Using Annexin V- propidium iodide staining, we found that CUDC-907 induced cell death by apoptosis after 24 hrs at low concentration (0.1 μM) in three representative DLBCL cell lines, SUDHL-6 (GCB), HBL-1 (ABC) and NUDHL-1 (DHL), but was ineffective in the Hodgkin lymphoma (HL) cell line KMH-2 (Figure 1C). This evidence concerns the gene ANXA5 and diffuse large B-cell lymphoma.