The following covariates were tested: age, sex, witnessed arrest, initial rhythm, time arrest to ROSC, history of previous diseases, cardiac arrest etiology, vital sign (blood pressure, heart rate, respiration rate, temperature) at 48 hr after CA, APACHE II, the level of NSE, MAPK3, BCL2 and AKT1 at 48 hr after CA. Here, AKT1 is linked to cardiac arrest.