VEGFA and hepatocellular carcinoma: In summary, this study investigated the association of VEGFA -936C>T, -634G>C, -1612 G/A and -2578C>A polymorphisms with risk and clinical outcome of HCC simultaneously in the same cohort patients and found the VEGFA -2578C>A polymorphism was associated with a significantly decreased HCC risk and improved OS of resected HCC patients.