Gene expression was significantly decreased in tumor tissues for all 3 genes (t-testp-values: 9.4 × 10−6, 7.1 × 10−6, and 0.0013 for DTX1, BANK1, and BIN2, respectively), and DNA methylation was present in significantly more tumor samples (Fisher exact test p-values: 0.105, < 0.0001, and 0.0006 for DTX1, BANK1, and BIN2, respectively). The gene discussed is DTX1; the disease is neoplasm.