Western blot showed that miR-519d transfection in ovarian carcinoma cells downregulated RhoC (Ras homolog gene family member C), Bcl-2, cyclin D1, survivin, MMP2, MMP9, STAT3 (signal transducer and activator of transcription 3), and HuR (ELAV-like RNA-binding protein 1) expression (Figure 5A, P < 0.05). This evidence concerns the gene RHOC and ovarian carcinoma.