Tung and co-workers [38] tested a 25-gene-panel on 1781 breast cancer patients who were referred for BRCA1/2 gene testing at Myriad Genetics [35] and found that 9.3% of the patients harboured a mutation in the BRCA1/2 genes, but 4.2% of the patients carried a mutation in 14 additional genes. The gene discussed is BRCA1; the disease is breast carcinoma.