SOCS1 and primary biliary cholangitis: Comparably, the expressions of the SOCS1 gene and the SOCS1 protein were significantly suppressed in both PBC (0.5 ± 0.08 vs. 1.6 ± 0.6, p = 0.002 vs. controls, and 0.2 ± 0.04 vs. 1.8 ± 0.6; p = 0.005 vs. controls) and PSC (0.06 ± 0.01 vs. 1.6 ± 0.6, p = 0.0003 vs. controls, and 0.3 ± 0.02 vs. 1.8 ± 0.6; p = 0.001 vs. controls, respectively) (Figure 5C,D).