Adamts18 KO mice demonstrated higher tumor incidence rates and more tumor numbers than WT littermates (macroscopic polyps, WT vs. KO, 71% vs. 100%; tumor numbers, WT vs. KO, 1.5 ± 1 vs. 6.5 ± 1.9; n = 7/group, P = 0.0026) (Figure 2C). The gene discussed is ADAMTS18; the disease is neoplasm.