Human umbilical cord mesenchymal stem cells (HucMSCs) and gastric cancer-derived mesenchymal stem cells (GC-MSCs) were successfully isolated, cultured and characterized as previously described [16].In order to explore whether IL-17B has an effect on MSCs and further influences tumor progression, the hucMSCs and GC-MSCs were treated with rIL-17B for 48 hours, and washed with PBS for two times and incubated for another 48 hours, then this conditioned media was collected. This evidence concerns the gene IL17B and neoplasm.