Whether induction of Bex genes is specific to curcumin-mediated N2a cell apoptosis or a general consequence of apoptosis by any anti-cancer agent, we utilized both curcumin and 8-Methoxypyrimido [4′,5′:4,5]thieno(2,3-b) Quinoline-4(3 H)-One (MPTQ) to induce Bex genes. This evidence concerns the gene BEX3 and cancer.