POU2F3 and cancer: Although the physiological roles of LysoPS in the fields of oncology remain to be elucidated, the immune-suppressive properties of LysoPS that have been reported in several fields other than oncology (43–45) suggest that LysoPS might be involved in the immunological escape that is observed in cancers; when several cancer cells undergo apoptosis, PS is flipped outside the cell membrane and is converted into LysoPS by PS-PLA1, possibly suppressing immunological attacks to other living cancer cells in tumor tissues.