Considering that the LysoPA and ATX levels are known to be elevated in cirrhosis (51), the present results should be carefully interpreted when comparing the concentrations between the two groups; for example, the finding that the LysoPA level after adjustment according to the ALB level was lower in the gastric cancer group does not necessarily mean that the LysoPA might not be involved in the pathogenesis of gastric cancer. The gene discussed is ENPP2; the disease is gastric cancer.