Two of them FCER1G, and TYROBP are hubs in 3 cohorts: uHC, RO-T1D, and RO + IL-1RA; DUSP6, is a hub in both RO-T1D and LRS; and OAS2, HERC5, are hubs in both UHC and HRS. This evidence concerns the gene OAS2 and type 1 diabetes mellitus.