HMOX1 and cancer: We assessed tumor cell proliferation, microvessel density, and expression of human antigen (Hu)R, vascular endothelial growth factor (VEGF)-A, cyclooxygenase (COX)-2, and hemeoxygenase (HO)-1 for the following reasons: (1) HuR expression was suppressed by GTP in leukemia cells [21]; (2) HuR expression was positively associated with expression of VEGF-A, COX-2, and HO-1 [22–24]; and (3) these cancer-related molecules play important roles in malignant aggressiveness, including cell proliferation and angiogenesis in various types of cancer [25–27].