1993) and an elevated risk of coronary artery disease (Masuda et al. 2011; Mori et al. 2013). Microsomal triglyceride transfer protein (MTP) catalyzes the transfer of the lipids to apoB48 in endoplasmic reticulum lumen to assemble chylomicrons. In addition, MTP binds to nascent apoB48 to prevent dislocation from the endoplasmic reticulum and avoid proteosomal degradation (Hussain et al. 2003; Pal et al. 2005). The gene discussed is MTTP; the disease is coronary artery disorder.